Major Depression
- I Found The Way Out !
By Bob Ong BA
When I was about 10 years of age, I was saddened to lose one of my older brothers to suicidal depression and another is still suffering paranoia schizophrenia to this day. Yes, I wanted answers. I gained some insight after studying abnormal psychology at university. Then In 1983, I was struck with Major Depression with Chronic Fatigue. Yes I felt helpless and hopeless and most of the time totally debilitated in bed. Medical specialists with their prescription medicines brought little relief but an alternative treatment brought me back to my bubbly self. Since then, I have had 3 lapses until I found the ultimate biochemical solution in 2006. I have since helped friends and 2 family members recover from this dreadful debilitating health condiition.
My personal experiences with Severe Depression with Chronic Fatigue has convinced me that one of its causes has to do with inborn defective genes of brain cells and the nervous system whereby a stressful event can easily weaken the "power plants" called mitochondria found in each brain neuron. Just as a flat car battery can stall a flash looking car, the brain, central nervous system and autonomic nervous system can also malfunction thus affecting brain, organs and body functioning. This occurs when there are deficient amounts of neurotransmitters synthesised and when they fall below the critical levels, a person will experience a wide range of symptoms such as depression, negative thinking to suicidal thoughts, immune dysfunctioning, no appetite, sleeplessness, debilitating fatigue, headaches and bodily aches and even organ/s dysfunctioning. I shall call it Acute Neurotransmitters Deficiency Syndrome (ANDS). Logically, the severity of one's depression with chronic fatigue correspond to the level of neurotransmitters deficiencies.
By working out my recovery retrospectively, I discovered that the deficiences of the essential co-enzymes Q10 and NADH in the "power houses" or mitochondria were not enabling my brain cells to produce neurotransmitters sufficiently to cope with the stresses of life. Thus the solution to take bioavailable supplements of the co-enzymes Q10 and NADH led to speedy recovery within a month. Therefore, it is reasonable to conclude that these 2 coenzymes that could cross the "blood brain barrier" into every nerve cells of the brain have empowered the mitochondria to produce more cellular energy to the "factories" or ribosomes to synthesise more neurotransmitters!!!
Scientists have established that the trillions of brain cells require two important "fuels" to make them work. They are the coenzymes Q10 and NADH. Interestingly our brain can synthesise these molecules daily but inborn defective genes and stressful events can affect production of these fuels. Also the demands of daily life can deplete their supplies faster than their production hence causing deficiency. Thus, when their quantities become low, the synthesis of neurotransmitters also become less leading to ANDS. Like a flat battery that stalls a car, an ANDS sufferer can stay in this condition for years without effective treatment. The good news is bioavailable Q10 and NADH supplements are made available by scientific processing and thus they can be orally taken to get the brain cells' "powerhouses" firing to full capacity again!
The Homeostasis Factor
Once the celllular energy part is take care of, we need to know that our nervous system works by excitation and inhibition and then returning to stable equilibrium condition called homeostasis. For example, food in the stomach will activate gastric juice release after which it stops when the stomach is empty. Due to genetic reasons, some of us have difficulty getting the inhibition side to work so we remain on "excitation mode" which uses up a lot of neurotransmitters and our brains are still very active even though we may feel very fatigued. Then nights of "sleep debt" will contribute to further neurotransmitters deficiences leading to Acute Neurotransmitters Deficiencies Syndrome (ANDS). Fortunately, sedative medications like lorazepam can arrest this trend. For mild cases, some dietary supplements like valerian or lactium can be effective. As mine is very serious, I take my lorazepam daily to maintain homeostasis of my nervious system just as a diabetic takes his insulin daily for life. It's good my doctor is understanding
The ANDS Solution
Multivitamin + Q10 + NADH + Sedative
(75mg daily) (10mg daily) (if necessary)
(I purchase my Q10 from Healthpost NZ and NADH from Birkmayer NADH USA )
Scientific Backing and Clinical Studies
Clinical studies of those taking NADH supplements have shown increased brain activity (see SPECT PHOTOS). Also clinical studies with 205 depressed patients saw an increase production of the neurotransmitters serotonin, dopomine and noradrenalin. My friend's wife who suffered severe postnatal depression for 9 years and on maximum dosage of SSRI antidepressants, recovered completely within 2 months using my formula without sedative in 2006. She came off the antidepressants easily with no withdrawal symptoms. Her good friend with bipolar disorder also fully recovered. While SSRI builds up concentration of serotonin in the brain after a few weeks, my formula boosts not only serotonin production to normal levels but also the countless of other types of neurotranmitters for the brain to function normally.
Notice the role of NADH in the production of cellular energy called ATP (adenosine triphosphate) in the animated diagrams below: (courtesy of Prof Terry of University of Connecticut,US)
My personal experiences with Major Depression with Chronic Fatigue, hundreds of hours of internet research and successes of those using my ANDS Solution speak volumes. This solution targets the nerve cells of the brain and the nervous system. I have experienced the worst depression with chronic fatigue possibly experienced by anyone. Now I live a vibrant productive life. I am still predisposed to this condition but I take my formula daily and this has enabled me stay on top of it. This simple solution can be liken to sailors in the past that died from scurvy but those that took lemons containing vitamin C recovered miraculously! I always remember that it wasn't a scientist that discovered the chromosomes and genes; it was a highly intelligent priest and therefore I have a say on this subject!!
Bob Ong, Wellington, NZ
Contact: okybob@yahoo.com
Author is not responsible for sedative abuses.